![]() In this review, we discuss the relationship between sleep and COVID-19 in older adults. There has been less discussion about the specific sleep patterns and prevalence of sleep disorders in older adults, which might mediate the increased severity of COVID-19 in this population. The relationship between sleep disorders and COVID-19 has already been discussed but has mostly focused on the general population ( Agoramoorthy et al., 2020 Altena et al., 2020 De Mello et al., 2020 Jahrami et al., 2020 Meira E Cruz et al., 2020 Morin et al., 2020 Roitblat et al., 2021). In this review, we discuss the relationship between sleep and COVID-19 among older adults, focusing on three different aspects: (1) Sleep-related issues that might increase the likelihood of getting infected by SARS-COV-2 (2) Sleep disturbances that might increase the predisposition to worse COVID-19 prognosis and outcomes and (3) COVID-19-related aspects affecting community-dwelling older adults, such as social isolation, quarantine, and home confinement, among others, that might impact sleep. We believe that the intrinsic sleep patterns of older adults, and the prevalence of sleep disorders in this population, may be important factors that could explain why they are at a greater risk of negative COVID-19 outcomes. Previous research has already linked sleep disorders (especially sleep apnea) with COVID-19, but few studies have focused specifically on the older population. Additionally, an increased prevalence of sleep disorders can be observed, such as obstructive sleep apnea and insomnia. In older adults a specific sleep profile can be observed, one characterized by advanced sleep timing, a morningness preference, longer sleep-onset latency, shorter overall sleep duration, increased sleep fragmentation, reduced slow-wave sleep and, increased wake time after sleep onset. An individual’s sleep pattern undergoes significant changes over the course of their life. Research has focused on the reasons why older adults are at greater risk Sleep-related factors have been suggested as one possible explanation for this. ![]() Since the beginning of the COVID-19 pandemic, older adults have been found to be a highly vulnerable group, with a higher prevalence of severe cases and negative outcomes. ![]() 3Programa de Pós-Graduação em Medicina Translacional, Universidade Federal de São Paulo, São Paulo, Brazil.2Department of Otolaryngology, Santa Casa de São Paulo, São Paulo, Brazil.1Departamento de Psicobiologia, Universidade Federal de São Paulo, São Paulo, Brazil.Gabriel Natan Pires 1* Isabela Antunes Ishikura 1 Sandra Doria Xavier 1,2 Caetano Petrella 1 Ronaldo Delmonte Piovezan 1 Ellen Maria Sampaio Xerfan 3 Monica Levy Andersen 1 Sergio Tufik 1 ![]()
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